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acantholysis.

The loss of intercellular connections, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris.

12 characters5 syllables approx.English language

Meaning & usage

noun/æˌkænˈθɒ.lɪs.ɪs/UK/æˌkænˈθɑ.lə.sɪs/US
  1. The loss of intercellular connections, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris.

    uncountable · usually
Where this word comes from

From acanth- (“spine”) + -lysis (“destruction”).

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Definitions, grammatical labels, IPA, etymology and examples: Wiktionary contributors, extracted by Kaikki / Wiktextract. Adapted under CC BY-SA 4.0. Selected fields and authored examples are shown; third-party quotations and audio are omitted. See contributor history.

Last enriched 2026-09-10. Definitions are in English. Romanizations are shown when supplied by the source; syllable estimates are omitted for unsupported scripts.