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methylation.

The addition of a methyl group to a molecule.

11 characters4 syllables approx.English language

Meaning & usage

noun/ˌmɛθɪˈleɪʃən/
  1. The addition of a methyl group to a molecule.

    countable · uncountable
  2. The addition of a methyl group to cytosine and adenine residues in DNA that leads to the epigenetic modification of DNA and the reduction of gene expression and protein production.

    countable · uncountable
Where this word comes from

Etymology tree Proto-Indo-European *médʰu Proto-Hellenic *métʰu Ancient Greek μέθυ (méthu) Proto-Indo-European *swel-der.? Ancient Greek ῡ̔́λη (hū́lē)der. German -yl German Methylbor. English methyl Proto-Indo-European *-tis Proto-Indo-European *-Hō Proto-Indo-European *-tiHō Proto-Italic *-tiō Latin -tiō Latin -ātiōlbor. Old French -ationbor. Middle English -acioun English -ation English methylation From methyl + -ation.

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Definitions, grammatical labels, IPA, etymology and examples: Wiktionary contributors, extracted by Kaikki / Wiktextract. Adapted under CC BY-SA 4.0. Selected fields and authored examples are shown; third-party quotations and audio are omitted. See contributor history.

Last enriched 2026-09-10. Definitions are in English. Romanizations are shown when supplied by the source; syllable estimates are omitted for unsupported scripts.