propositus.
The first identified male case of an inherited disease in a family; the proband or index case.
Meaning & usage
The first identified male case of an inherited disease in a family; the proband or index case.
The propositus was an elderly man who passed on the disorder to three of his four children and 9 of 14 grandchildren.
Where this word comes from
Borrowed from Latin prōpositus.
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Definitions, grammatical labels, IPA, etymology and examples: Wiktionary contributors, extracted by Kaikki / Wiktextract. Adapted under CC BY-SA 4.0. Selected fields and authored examples are shown; third-party quotations and audio are omitted. See contributor history.
Last enriched 2026-09-10. Definitions are in English. Romanizations are shown when supplied by the source; syllable estimates are omitted for unsupported scripts.