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smallpox.

An acute, highly infectious often fatal disease caused by Variola virus of the family Poxviridae. It was completely eradicated in the 1970s, but still exists in laboratories. Those who survived were left with pockmarks.

8 characters2 syllables approx.English language

Meaning & usage

noun/ˈsmɔːlpɒks/Received-Pronunciation/ˈsmɔlpɑks/General-American
  1. An acute, highly infectious often fatal disease caused by Variola virus of the family Poxviridae. It was completely eradicated in the 1970s, but still exists in laboratories. Those who survived were left with pockmarks.

    uncountable · usually
    The Europeans brought new diseases such as smallpox, measles, dysentery, influenza, syphilis and leprosy.
Where this word comes from

From small + pox, in contrast to greatpox (“syphilis”).

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Definitions, grammatical labels, IPA, etymology and examples: Wiktionary contributors, extracted by Kaikki / Wiktextract. Adapted under CC BY-SA 4.0. Selected fields and authored examples are shown; third-party quotations and audio are omitted. See contributor history.

Last enriched 2026-09-10. Definitions are in English. Romanizations are shown when supplied by the source; syllable estimates are omitted for unsupported scripts.