variolation.
The inoculation of a person with smallpox with the intention of inducing a mild form of the illness and subsequent immunity to the disease.
Meaning & usage
The inoculation of a person with smallpox with the intention of inducing a mild form of the illness and subsequent immunity to the disease.
Variolation is no longer used today. It was replaced by smallpox vaccination, a safer alternative, which in turn led to the development of vaccines against many other diseases.
Where this word comes from
Etymology tree English variola Proto-Indo-European *-tis Proto-Indo-European *-Hō Proto-Indo-European *-tiHō Proto-Italic *-tiō Latin -tiō Latin -ātiōlbor. Old French -ationbor. Middle English -acioun English -ation English variolation From variola + -ation.
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Definitions, grammatical labels, IPA, etymology and examples: Wiktionary contributors, extracted by Kaikki / Wiktextract. Adapted under CC BY-SA 4.0. Selected fields and authored examples are shown; third-party quotations and audio are omitted. See contributor history.
Last enriched 2026-09-10. Definitions are in English. Romanizations are shown when supplied by the source; syllable estimates are omitted for unsupported scripts.